Drug Information

Drug General Information
Drug ID
DXLI4U
Drug Name
8-Chloro-11-(1-(propylsulfonyl)piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
Synonyms
CHEMBL3357031
Indication Discovery agent Investigative [1587926]
Formula
C22H25ClN2O2S
Canonical SMILES
CCCS(=O)(=O)N1CCC(=C2c3ccc(Cl)cc3CCc4cccnc24)CC1
InChI
InChI=1S/C22H25ClN2O2S/c1-2-14-28(26,27)25-12-9-16(10-13-25)21-20-8-7-19(23)15-18(20)6-5-17-4-3-11-24-22(17)21/h3-4,7-8,11,15H,2,5-6,9-10,12-14H2,1H3
InChIKey
MQRYPNWHTGJJKM-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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