Drug Information

Drug General Information
Drug ID
DXL5OT
Drug Name
N-Benzo[1,3]dioxol-5-yl-4-(3-bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N'-cyano-piperidine-1-carboxamidine
Synonyms
CHEMBL347003
Indication Discovery agent Investigative [1587926]
Formula
C28H23BrClN5O2
Canonical SMILES
Clc1ccc2C(=C3CCN(CC3)\\C(=N/c4ccc5OCOc5c4)\\NC#N)c6ncc(Br)cc6CCc2c1
InChI
InChI=1S/C28H23BrClN5O2/c29-20-11-19-2-1-18-12-21(30)3-5-23(18)26(27(19)32-14-20)17-7-9-35(10-8-17)28(33-15-31)34-22-4-6-24-25(13-22)37-16-36-24/h3-6,11-14H,1-2,7-10,16H2,(H,33,34)
InChIKey
ABTXIAMOBHCWMR-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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