Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXL02X
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| Drug Name |
1-(2-amino-6-(3,5-diethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl)-3-tert-butylurea
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| Synonyms |
CHEMBL48809
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C22H28N6O3
|
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| Canonical SMILES |
CCOc1cc(OCC)cc(c1)c2cc3cnc(N)nc3nc2NC(=O)NC(C)(C)C
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| InChI |
InChI=1S/C22H28N6O3/c1-6-30-15-8-13(9-16(11-15)31-7-2)17-10-14-12-24-20(23)26-18(14)25-19(17)27-21(29)28-22(3,4)5/h8-12H,6-7H2,1-5H3,(H4,23,24,25,26,27,28,29)
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| InChIKey |
ORGYAJJXKGASTK-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Basic fibroblast growth factor receptor 1 | Target Info | [1587926] | ||
| Platelet-derived growth factor receptor | Target Info | [1587926] | |||
| KEGG Pathway | MAPK signaling pathway | ||||
| Ras signaling pathway | |||||
| Rap1 signaling pathway | |||||
| PI3K-Akt signaling pathway | |||||
| Adherens junction | |||||
| Signaling pathways regulating pluripotency of stem cells | |||||
| Regulation of actin cytoskeleton | |||||
| Pathways in cancer | |||||
| Proteoglycans in cancer | |||||
| Prostate cancer | |||||
| Melanoma | |||||
| Central carbon metabolism in cancer | |||||
| NetPath Pathway | TCR Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| FGF signaling pathway | |||||
| Pathway Interaction Database | Glypican 1 network | ||||
| Syndecan-4-mediated signaling events | |||||
| N-cadherin signaling events | |||||
| FGF signaling pathway | |||||
| References | |||||
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