Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXK4LD
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| Drug Name |
9-Cyclopentyl-6-(2-{4-[2-(2-methoxy-ethylamino)-ethoxy]-benzyloxy}-phenylamino)-9H-purine-2-carbonitrile
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| Synonyms |
CHEMBL361499
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C29H33N7O3
|
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| Canonical SMILES |
COCCNCCOc1ccc(COc2ccccc2Nc3nc(nc4c3ncn4C5CCCC5)C#N)cc1
|
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| InChI |
InChI=1S/C29H33N7O3/c1-37-16-14-31-15-17-38-23-12-10-21(11-13-23)19-39-25-9-5-4-8-24(25)33-28-27-29(35-26(18-30)34-28)36(20-32-27)22-6-2-3-7-22/h4-5,8-13,20,22,31H,2-3,6-7,14-17,19H2,1H3,(H,33,34,35)
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| InChIKey |
MLAYQZHQPOWWIL-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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