Drug Information

Drug General Information
Drug ID
DXJ2GP
Drug Name
(S)-2-[3-(3-Methoxy-phenyl)-ureido]-5-oxo-5-pyrrolidin-1-yl-pentanoic acid dipentylamide
Synonyms
CHEMBL346070
Indication Discovery agent Investigative [1587926]
Formula
C27H44N4O4
Canonical SMILES
CCCCCN(CCCCC)C(=O)[C@@H](CCC(=O)N1CCCC1)NC(=O)Nc2cccc(OC)c2
InChI
InChI=1S/C27H44N4O4/c1-4-6-8-19-31(20-9-7-5-2)26(33)24(15-16-25(32)30-17-10-11-18-30)29-27(34)28-22-13-12-14-23(21-22)35-3/h12-14,21,24H,4-11,15-20H2,1-3H3,(H2,28,29,34)/t24-/m1/s1
InChIKey
DTSANQSRTBGPPK-XMMPIXPASA-N
Target and Pathway
Target(s) Gastrin/cholecystokinin type B receptor Target Info [1587926]
Cholecystokinin receptor type A Target Info [1587926]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gastric acid secretionhsa04020:Calcium signaling pathway
Insulin secretion
Pancreatic secretion
PANTHER Pathway CCKR signaling map ST
PathWhiz Pathway Gastric Acid Production
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
Gastrin-CREB signalling pathway via PKC and MAPKR-HSA-375276:Peptide ligand-binding receptors
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Secretion of Hydrochloric Acid in Parietal Cells
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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