Drug Information

Drug General Information
Drug ID
DXJ0IK
Drug Name
6-[(4-Cyano-phenyl)-thiazol-5-yl-methoxymethyl]-1-methyl-2-oxo-5-(4-trifluoromethoxy-phenyl)-1,2-dihydro-pyridine-3-carbonitrile
Synonyms
CHEMBL128573
Indication Discovery agent Investigative [1587926]
Formula
C26H17F3N4O3S
Canonical SMILES
CN1C(=C(C=C(C#N)C1=O)c2ccc(OC(F)(F)F)cc2)COC(c3ccc(cc3)C#N)c4cncs4
InChI
InChI=1S/C26H17F3N4O3S/c1-33-22(14-35-24(23-13-32-15-37-23)18-4-2-16(11-30)3-5-18)21(10-19(12-31)25(33)34)17-6-8-20(9-7-17)36-26(27,28)29/h2-10,13,15,24H,14H2,1H3
InChIKey
FPVFNTHWCRWGPI-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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