Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXH6GP
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| Drug Name |
4-(3-Adamantan-1-yl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-ylamino)-benzoic acid
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| Synonyms |
CHEMBL257577
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C21H22N6O2
|
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| Canonical SMILES |
OC(=O)c1ccc(Nc2ncc3nnn(c3n2)C45CC6CC(CC(C6)C4)C5)cc1
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| InChI |
InChI=1S/C21H22N6O2/c28-19(29)15-1-3-16(4-2-15)23-20-22-11-17-18(24-20)27(26-25-17)21-8-12-5-13(9-21)7-14(6-12)10-21/h1-4,11-14H,5-10H2,(H,28,29)(H,22,23,24)
|
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| InChIKey |
HZOKUCWZAVEKGI-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Aurora kinase A | Target Info | [1587926] | ||
| Glycogen synthase kinase-3 | Target Info | [1587926] | |||
| KEGG Pathway | Oocyte meiosis | ||||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
| Pathway Interaction Database | Aurora B signaling | ||||
| Signaling by Aurora kinases | |||||
| Integrin-linked kinase signaling | |||||
| PLK1 signaling events | |||||
| Aurora A signalingbetacatenin_deg_pathway:Degradation of beta catenin | |||||
| Canonical Wnt signaling pathway | |||||
| FOXM1 transcription factor network | |||||
| Class I PI3K signaling events mediated by Akt | |||||
| References | |||||
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