Drug Information

Drug General Information
Drug ID
DXH5MN
Drug Name
4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-cycloheptanecarbonyl-piperazine-2-carboxylic acid (pyridin-3-ylmethyl)-amide
Synonyms
CHEMBL201888
Indication Discovery agent Investigative [1587926]
Formula
C33H37BrClN5O2
Canonical SMILES
Clc1ccc2C(N3CCN(C(C3)C(=O)NCc4cccnc4)C(=O)C5CCCCCC5)c6ncc(Br)cc6CCc2c1
InChI
InChI=1S/C33H37BrClN5O2/c34-26-16-25-10-9-24-17-27(35)11-12-28(24)31(30(25)37-20-26)39-14-15-40(33(42)23-7-3-1-2-4-8-23)29(21-39)32(41)38-19-22-6-5-13-36-18-22/h5-6,11-13,16-18,20,23,29,31H,1-4,7-10,14-15,19,21H2,(H,38,41)
InChIKey
VCIMPMYMNFFUID-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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