Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXG8DU
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| Drug Name |
[(3-Bromophenyl)-(3-acetoxyphenyl)-ketone]thiosemicarbazone
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| Synonyms |
CHEMBL1272261
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C16H14BrN3O2S
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| Canonical SMILES |
CC(=O)Oc1cccc(c1)\\C(=N/NC(=S)N)\\c2cccc(Br)c2
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| InChI |
InChI=1S/C16H14BrN3O2S/c1-10(21)22-14-7-3-5-12(9-14)15(19-20-16(18)23)11-4-2-6-13(17)8-11/h2-9H,1H3,(H3,18,20,23)/b19-15-
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| InChIKey |
AVVBLEPNUHTRSC-CYVLTUHYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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