Drug Information

Drug General Information
Drug ID
DXG0WL
Drug Name
1-[4-(8-Chloro-11H-10-thia-4-aza-dibenzo[a,d]cyclohepten-5-ylidene)-piperidin-1-yl]-2-(1-oxy-pyridin-4-ylsulfanyl)-ethanone
Synonyms
CHEMBL315599
Indication Discovery agent Investigative [1587926]
Formula
C25H22ClN3O2S2
Canonical SMILES
[O-][n+]1ccc(SCC(=O)N2CCC(=C3c4ccc(Cl)cc4SCc5cccnc35)CC2)cc1
InChI
InChI=1S/C25H22ClN3O2S2/c26-19-3-4-21-22(14-19)33-15-18-2-1-9-27-25(18)24(21)17-5-10-28(11-6-17)23(30)16-32-20-7-12-29(31)13-8-20/h1-4,7-9,12-14H,5-6,10-11,15-16H2
InChIKey
HVTQOXXHYUJBJU-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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