Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXFL7E
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| Drug Name |
(S)-N-((R)-2-(benzyloxy)-1-cyanoethyl)-4-methyl-2-(2-(4-(pyridin-4-yl)piperazin-1-yl)acetamido)pentanamide
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| Synonyms |
CHEMBL207560
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C27H36N6O3
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| Canonical SMILES |
CC(C)C[C@H](NC(=O)CN1CCN(CC1)c2ccncc2)C(=O)N[C@@H](COCc3ccccc3)C#N
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| InChI |
InChI=1S/C27H36N6O3/c1-21(2)16-25(27(35)30-23(17-28)20-36-19-22-6-4-3-5-7-22)31-26(34)18-32-12-14-33(15-13-32)24-8-10-29-11-9-24/h3-11,21,23,25H,12-16,18-20H2,1-2H3,(H,30,35)(H,31,34)/t23-,25+/m1/s1
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| InChIKey |
UZCUBOSCRIAKSH-NOZRDPDXSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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