TTD | Drug: DXFB5K

Drug General Information
Drug ID	DXFB5K
Drug Name	4-phenyl-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetrahydro-2,6-naphthyridine
Synonyms	CHEMBL247062
Indication	Discovery agent		Investigative	[1587926]
Formula	C22H29N3O
Canonical SMILES	C(COc1cc2CNCC(c3ccccc3)c2cn1)CN4CCCCC4
InChI	InChI=1S/C22H29N3O/c1-3-8-18(9-4-1)20-16-23-15-19-14-22(24-17-21(19)20)26-13-7-12-25-10-5-2-6-11-25/h1,3-4,8-9,14,17,20,23H,2,5-7,10-13,15-16H2
InChIKey	UFTSHWLSGKIRED-UHFFFAOYSA-N
Target and Pathway
Target(s)	Histamine H3 receptor	Target Info		[1587926]
Target(s)	Sodium-dependent serotonin transporter	Target Info		[1587926]
KEGG Pathway	Neuroactive ligand-receptor interactionhsa04726:Serotonergic synapse
NetPath Pathway	TCR Signaling Pathway
PANTHER Pathway	5HT1 type receptor mediated signaling pathway
	5HT2 type receptor mediated signaling pathway
	5HT3 type receptor mediated signaling pathway
	5HT4 type receptor mediated signaling pathway
Reactome	Histamine receptors
Reactome	G alpha (i) signalling events
WikiPathways	Monoamine Transport
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signalingWP727:Monoamine Transport
	SIDS Susceptibility Pathways
	NRF2 pathway
	Synaptic Vesicle Pathway
	Serotonin Transporter Activity
References
Ref 1587926	URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926	URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.

Drug Information