Drug General Information
Drug ID
DXF9MB
Drug Name
R-Diastereomer A-2-(3-chlorophenyl)-27-oxo-20-oxa-3,7,11,13-tetraazapentacyclo[19.3.1.13,6.115,19.09,13]heptacosa-1(24),9,11,15(26),16,18,21(25),22-octaen-18-yl cyanide
Synonyms
CHEMBL312034
Indication Discovery agent Investigative [1587926]
Formula
C29H24ClN5O2
Canonical SMILES
Clc1cccc(c1)C2N3CCC(NCc4cncn4Cc5ccc(C#N)c(Oc6cccc2c6)c5)C3=O
InChI
InChI=1S/C29H24ClN5O2/c30-23-5-1-3-20(12-23)28-21-4-2-6-25(13-21)37-27-11-19(7-8-22(27)14-31)17-34-18-32-15-24(34)16-33-26-9-10-35(28)29(26)36/h1-8,11-13,15,18,26,28,33H,9-10,16-17H2
InChIKey
MVPXMHNFAQUXRM-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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