Drug Information

Drug General Information
Drug ID
DXE66E
Drug Name
1-[4-(8-Chloro-10,10-dioxo-10,11-dihydro-10lambda*6*-thia-4-aza-dibenzo[a,d]cyclohepten-5-ylidene)-piperidin-1-yl]-2-pyridin-4-yl-ethanone
Synonyms
CHEMBL82004
Indication Discovery agent Investigative [1587926]
Formula
C25H22ClN3O3S
Canonical SMILES
Clc1ccc2C(=C3CCN(CC3)C(=O)Cc4ccncc4)c5ncccc5CS(=O)(=O)c2c1
InChI
InChI=1S/C25H22ClN3O3S/c26-20-3-4-21-22(15-20)33(31,32)16-19-2-1-9-28-25(19)24(21)18-7-12-29(13-8-18)23(30)14-17-5-10-27-11-6-17/h1-6,9-11,15H,7-8,12-14,16H2
InChIKey
WBPFFIOJPTYZOL-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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