Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXE0WY
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| Drug Name |
2-{(S)-3-Phenyl-1-[(4-piperidin-1-yl-phenylamino)-methyl]-propylcarbamoyl}-pyrrolidine-1-carboxylic acid benzyl ester
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| Synonyms |
CHEMBL170962
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C34H42N4O3
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| Canonical SMILES |
O=C(N[C@@H](CCc1ccccc1)CNc2ccc(cc2)N3CCCCC3)C4CCCN4C(=O)OCc5ccccc5
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| InChI |
InChI=1S/C34H42N4O3/c39-33(32-15-10-24-38(32)34(40)41-26-28-13-6-2-7-14-28)36-30(17-16-27-11-4-1-5-12-27)25-35-29-18-20-31(21-19-29)37-22-8-3-9-23-37/h1-2,4-7,11-14,18-21,30,32,35H,3,8-10,15-17,22-26H2,(H,36,39)/t30-,32?/m0/s1
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| InChIKey |
LZKLRYNDKQXBDX-TZYYSAMKSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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