Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXDN7C
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| Drug Name |
(S)-N-(cyanomethyl)-4-fluoro-4-methyl-2-((S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)biphenyl-4-yl)ethylamino)pentanamide
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| Synonyms |
CHEMBL1289441
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C23H25F4N3O3S
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| Canonical SMILES |
CC(C)(F)C[C@H](N[C@@H](c1ccc(cc1)c2ccc(cc2)S(=O)(=O)C)C(F)(F)F)C(=O)NCC#N
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| InChI |
InChI=1S/C23H25F4N3O3S/c1-22(2,24)14-19(21(31)29-13-12-28)30-20(23(25,26)27)17-6-4-15(5-7-17)16-8-10-18(11-9-16)34(3,32)33/h4-11,19-20,30H,13-14H2,1-3H3,(H,29,31)/t19-,20-/m0/s1
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| InChIKey |
UYDFFWBONYOJKU-PMACEKPBSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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