Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXD8LF
|
||||
| Drug Name |
N-(1-((cyanomethyl)carbamoyl)cyclohexyl)-3-bromobenzamide
|
||||
| Synonyms |
CHEMBL200482
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C16H18BrN3O2
|
||||
| Canonical SMILES |
Brc1cccc(c1)C(=O)NC2(CCCCC2)C(=O)NCC#N
|
||||
| InChI |
InChI=1S/C16H18BrN3O2/c17-13-6-4-5-12(11-13)14(21)20-16(7-2-1-3-8-16)15(22)19-10-9-18/h4-6,11H,1-3,7-8,10H2,(H,19,22)(H,20,21)
|
||||
| InChIKey |
CYZWWELYRDUUFA-UHFFFAOYSA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.