Drug Information
| Drug General Information | |||||
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| Drug ID |
DXD5GU
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| Drug Name |
19-methyl-7-[(thiophen-2-yl)carbonyl]-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-14-one
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| Synonyms |
CHEMBL428876
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C25H18N4O2S
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| Canonical SMILES |
Cn1cc2c(CCc3c2c4C(=O)NCc4c5c6cc(ccc6[nH]c35)C(=O)c7cccs7)n1
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| InChI |
InChI=1S/C25H18N4O2S/c1-29-11-16-18(28-29)7-5-13-20(16)22-15(10-26-25(22)31)21-14-9-12(4-6-17(14)27-23(13)21)24(30)19-3-2-8-32-19/h2-4,6,8-9,11,27H,5,7,10H2,1H3,(H,26,31)
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| InChIKey |
VOZWUTXGVBZOLP-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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