Drug Information

Drug General Information
Drug ID
DXD1LI
Drug Name
4-{5-[4-(3-Chloro-phenyl)-3-oxo-piperazin-1-ylmethyl]-imidazol-1-ylmethyl}-2-(pyridin-3-yloxy)-benzonitrile
Synonyms
CHEMBL30270
Indication Discovery agent Investigative [1587926]
Formula
C27H23ClN6O2
Canonical SMILES
Clc1cccc(c1)N2CCN(Cc3cncn3Cc4ccc(C#N)c(Oc5cccnc5)c4)CC2=O
InChI
InChI=1S/C27H23ClN6O2/c28-22-3-1-4-23(12-22)34-10-9-32(18-27(34)35)17-24-14-31-19-33(24)16-20-6-7-21(13-29)26(11-20)36-25-5-2-8-30-15-25/h1-8,11-12,14-15,19H,9-10,16-18H2
InChIKey
YRERXVCECMZRBL-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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