Drug Information

Drug General Information
Drug ID
DXB4HR
Drug Name
1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidine-1-sulfonylmethyl]-7,7-dimethyl-bicyclo[2.2.1]heptan-2-ol
Synonyms
CHEMBL444325
Indication Discovery agent Investigative [1587926]
Formula
C29H35ClN2O3S
Canonical SMILES
CC1(C)C2CCC1(CS(=O)(=O)N3CCC(=C4c5ccc(Cl)cc5CCc6cccnc46)CC3)C(O)C2
InChI
InChI=1S/C29H35ClN2O3S/c1-28(2)22-9-12-29(28,25(33)17-22)18-36(34,35)32-14-10-19(11-15-32)26-24-8-7-23(30)16-21(24)6-5-20-4-3-13-31-27(20)26/h3-4,7-8,13,16,22,25,33H,5-6,9-12,14-15,17-18H2,1-2H3
InChIKey
HIXYSZMUDQIMOT-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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