Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXB3O5
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| Drug Name |
2-((3,5-bis(trifluoromethyl)phenyl)(p-tolyl)methylene)hydrazinecarbothioamide
|
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| Synonyms |
CHEMBL521727
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C17H13F6N3S
|
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| Canonical SMILES |
Cc1ccc(cc1)\\C(=N\\NC(=S)N)\\c2cc(cc(c2)C(F)(F)F)C(F)(F)F
|
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| InChI |
InChI=1S/C17H13F6N3S/c1-9-2-4-10(5-3-9)14(25-26-15(24)27)11-6-12(16(18,19)20)8-13(7-11)17(21,22)23/h2-8H,1H3,(H3,24,26,27)/b25-14-
|
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| InChIKey |
KQRXZKZSIDZXHU-QFEZKATASA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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