Drug Information

Drug General Information
Drug ID
DXB2VG
Drug Name
4-{2-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-oxo-ethyl}-piperidine-1-carboxylic acid amide
Synonyms
CHEMBL358796
Indication Discovery agent Investigative [1587926]
Formula
C26H30Br2ClN5O2
Canonical SMILES
NC(=O)N1CCC(CC(=O)N2CCN(CC2)[C@H]3c4ncc(Br)cc4CCc5cc(Cl)cc(Br)c35)CC1
InChI
InChI=1S/C26H30Br2ClN5O2/c27-19-12-18-2-1-17-13-20(29)14-21(28)23(17)25(24(18)31-15-19)33-9-7-32(8-10-33)22(35)11-16-3-5-34(6-4-16)26(30)36/h12-16,25H,1-11H2,(H2,30,36)/t25-/m1/s1
InChIKey
YQYGDEQYTHPZGX-RUZDIDTESA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.