Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXAN5L
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| Drug Name |
N-Cyanomethyl-2-[4'-(4-methyl-piperazin-1-yl)-biphenyl-3-yl]-3-phenyl-propionamide
|
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| Synonyms |
CHEMBL332776
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C28H30N4O
|
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| Canonical SMILES |
CN1CCN(CC1)c2ccc(cc2)c3cccc(c3)C(Cc4ccccc4)C(=O)NCC#N
|
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| InChI |
InChI=1S/C28H30N4O/c1-31-16-18-32(19-17-31)26-12-10-23(11-13-26)24-8-5-9-25(21-24)27(28(33)30-15-14-29)20-22-6-3-2-4-7-22/h2-13,21,27H,15-20H2,1H3,(H,30,33)
|
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| InChIKey |
MILUUTXLDNUOSK-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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