Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX9TXT
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| Drug Name |
(S)-1-(5,6-dichloro-1H-benzo[d]imidazol-1-yl)-3,3-dimethylbutan-2-yl (S)-2-oxo-1-(pyridine-2-sulfonamido)heptan-3-ylcarbamate
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| Synonyms |
CHEMBL232713
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C26H33Cl2N5O5S
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| Canonical SMILES |
CCCC[C@H](NC(=O)O[C@H](Cn1cnc2cc(Cl)c(Cl)cc12)C(C)(C)C)C(=O)CNS(=O)(=O)c3ccccn3
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| InChI |
InChI=1S/C26H33Cl2N5O5S/c1-5-6-9-19(22(34)14-31-39(36,37)24-10-7-8-11-29-24)32-25(35)38-23(26(2,3)4)15-33-16-30-20-12-17(27)18(28)13-21(20)33/h7-8,10-13,16,19,23,31H,5-6,9,14-15H2,1-4H3,(H,32,35)/t19-,23+/m0/s1
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| InChIKey |
CTAIZAPBSQNUAF-WMZHIEFXSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | RANKL/RANK Signaling Pathway | ||||
| Osteoclast Signaling | |||||
| References | |||||
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