Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX9GKX
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| Drug Name |
N-(4-fluoro-3-(3-(4-(methylamino)-1,3,5-triazin-2-yl)pyridin-2-yloxy)phenyl)-3-isopropylbenzamide
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| Synonyms |
CHEMBL394694
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C25H23FN6O2
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| Canonical SMILES |
CNc1ncnc(n1)c2cccnc2Oc3cc(NC(=O)c4cccc(c4)C(C)C)ccc3F
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| InChI |
InChI=1S/C25H23FN6O2/c1-15(2)16-6-4-7-17(12-16)23(33)31-18-9-10-20(26)21(13-18)34-24-19(8-5-11-28-24)22-29-14-30-25(27-3)32-22/h4-15H,1-3H3,(H,31,33)(H,27,29,30,32)
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| InChIKey |
NXSKYUVQJMCLKI-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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