Drug Information

Drug General Information
Drug ID
DX9FDB
Drug Name
3-(4-Iodo-phenyl)-8-methoxycarbonylmethyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester
Synonyms
CHEMBL149801
Indication Discovery agent Investigative [1587926]
Formula
C18H22INO4
Canonical SMILES
COC(=O)CN1C2CCC1C(C(C2)c3ccc(I)cc3)C(=O)OC
InChI
InChI=1S/C18H22INO4/c1-23-16(21)10-20-13-7-8-15(20)17(18(22)24-2)14(9-13)11-3-5-12(19)6-4-11/h3-6,13-15,17H,7-10H2,1-2H3
InChIKey
LHGWXWFENXILDS-UHFFFAOYSA-N
Target and Pathway
Target(s) Sodium-dependent noradrenaline transporter Target Info [1587926]
Sodium-dependent serotonin transporter Target Info [1587926]
KEGG Pathway Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Adrenaline and noradrenaline biosynthesisP04373:5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
NRF2 pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsWP727:Monoamine Transport
SIDS Susceptibility Pathways
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.