Drug Information

Drug General Information
Drug ID
DX8TRP
Drug Name
4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N-(4-methanesulfonyl-phenyl)-N'-cyano-piperidine-1-carboxamidine
Synonyms
CHEMBL434857
Indication Discovery agent Investigative [1587926]
Formula
C28H25BrClN5O2S
Canonical SMILES
CS(=O)(=O)c1ccc(N\\C(=N/C#N)\\N2CCC(=C3c4ccc(Cl)cc4CCc5cc(Br)cnc35)CC2)cc1
InChI
InChI=1S/C28H25BrClN5O2S/c1-38(36,37)24-7-5-23(6-8-24)34-28(33-17-31)35-12-10-18(11-13-35)26-25-9-4-22(30)15-19(25)2-3-20-14-21(29)16-32-27(20)26/h4-9,14-16H,2-3,10-13H2,1H3,(H,33,34)
InChIKey
ZXZCZXFBPDNZLF-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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