Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX8TMT
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| Drug Name |
methyl 4-(6,7-dimethoxyquinazolin-4-ylamino)phenylcarbamate
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| Synonyms |
CHEMBL1761929
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C18H18N4O4
|
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| Canonical SMILES |
COC(=O)Nc1ccc(Nc2ncnc3cc(OC)c(OC)cc23)cc1
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| InChI |
InChI=1S/C18H18N4O4/c1-24-15-8-13-14(9-16(15)25-2)19-10-20-17(13)21-11-4-6-12(7-5-11)22-18(23)26-3/h4-10H,1-3H3,(H,22,23)(H,19,20,21)
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| InChIKey |
HNEAOQOOUVUUJR-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Epidermal growth factor receptor III | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathway | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY network | |||||
| References | |||||
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