Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX8IU9
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| Drug Name |
2-(2,6-dichlorophenylthio)-N-(5-methyl-1H-pyrazol-3-yl)quinazolin-4-amine
|
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| Synonyms |
CHEMBL561834
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C18H13Cl2N5S
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| Canonical SMILES |
Cc1cc(Nc2nc(Sc3c(Cl)cccc3Cl)nc4ccccc24)n[nH]1
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| InChI |
InChI=1S/C18H13Cl2N5S/c1-10-9-15(25-24-10)22-17-11-5-2-3-8-14(11)21-18(23-17)26-16-12(19)6-4-7-13(16)20/h2-9H,1H3,(H2,21,22,23,24,25)
|
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| InChIKey |
GYZHPLHOIMYBJI-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Aurora kinase A | Target Info | [1587926] | ||
| Glycogen synthase kinase-3 | Target Info | [1587926] | |||
| KEGG Pathway | Oocyte meiosis | ||||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
| Pathway Interaction Database | Aurora B signaling | ||||
| Signaling by Aurora kinases | |||||
| Integrin-linked kinase signaling | |||||
| PLK1 signaling events | |||||
| Aurora A signalingbetacatenin_deg_pathway:Degradation of beta catenin | |||||
| Canonical Wnt signaling pathway | |||||
| FOXM1 transcription factor network | |||||
| Class I PI3K signaling events mediated by Akt | |||||
| References | |||||
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