Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX7YRD
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| Drug Name |
(S)-N-((S)-1-cyano-3,3,3-trifluoropropyl)-4-fluoro-4-methyl-2-((S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)biphenyl-4-yl)ethylamino)pentanamide
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| Synonyms |
CHEMBL1289553
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C25H26F7N3O3S
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| Canonical SMILES |
CC(C)(F)C[C@H](N[C@@H](c1ccc(cc1)c2ccc(cc2)S(=O)(=O)C)C(F)(F)F)C(=O)N[C@@H](CC(F)(F)F)C#N
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| InChI |
InChI=1S/C25H26F7N3O3S/c1-23(2,26)13-20(22(36)34-18(14-33)12-24(27,28)29)35-21(25(30,31)32)17-6-4-15(5-7-17)16-8-10-19(11-9-16)39(3,37)38/h4-11,18,20-21,35H,12-13H2,1-3H3,(H,34,36)/t18-,20-,21-/m0/s1
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| InChIKey |
NNULPUWGQGOFSK-JBACZVJFSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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