Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX7RDT
|
||||
| Drug Name |
4-[4-(3-Hydroxy-adamantan-1-ylamino)-5-nitro-pyrimidin-2-ylamino]-benzoic acid
|
||||
| Synonyms |
CHEMBL402902
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C21H23N5O5
|
||||
| Canonical SMILES |
OC(=O)c1ccc(Nc2ncc(c(NC34CC5CC(CC(O)(C5)C3)C4)n2)[N+](=O)[O-])cc1
|
||||
| InChI |
InChI=1S/C21H23N5O5/c27-18(28)14-1-3-15(4-2-14)23-19-22-10-16(26(30)31)17(24-19)25-20-6-12-5-13(7-20)9-21(29,8-12)11-20/h1-4,10,12-13,29H,5-9,11H2,(H,27,28)(H2,22,23,24,25)
|
||||
| InChIKey |
YLVVCSCPLBFQFV-UHFFFAOYSA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Aurora kinase A | Target Info | [1587926] | ||
| Glycogen synthase kinase-3 | Target Info | [1587926] | |||
| KEGG Pathway | Oocyte meiosis | ||||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
| Pathway Interaction Database | Aurora B signaling | ||||
| Signaling by Aurora kinases | |||||
| Integrin-linked kinase signaling | |||||
| PLK1 signaling events | |||||
| Aurora A signalingbetacatenin_deg_pathway:Degradation of beta catenin | |||||
| Canonical Wnt signaling pathway | |||||
| FOXM1 transcription factor network | |||||
| Class I PI3K signaling events mediated by Akt | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.