Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX7CS4
|
||||
| Drug Name |
(S)-N-(3-(3-(1H-pyrazol-5-yl)phenyl)-1-(cyanomethylamino)-1-oxopropan-2-yl)benzamide
|
||||
| Synonyms |
CHEMBL563056
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C21H19N5O2
|
||||
| Canonical SMILES |
O=C(NCC#N)[C@H](Cc1cccc(c1)c2ccn[nH]2)NC(=O)c3ccccc3
|
||||
| InChI |
InChI=1S/C21H19N5O2/c22-10-12-23-21(28)19(25-20(27)16-6-2-1-3-7-16)14-15-5-4-8-17(13-15)18-9-11-24-26-18/h1-9,11,13,19H,12,14H2,(H,23,28)(H,24,26)(H,25,27)/t19-/m0/s1
|
||||
| InChIKey |
JIJXQXULSIMBGL-IBGZPJMESA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.