Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX6YGC
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| Drug Name |
N-Cyanomethyl-3-cyclopropyl-2-[4'-(4-methyl-piperazin-1-yl)-biphenyl-3-yl]-propionamide
|
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| Synonyms |
CHEMBL126210
|
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C25H30N4O
|
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| Canonical SMILES |
CN1CCN(CC1)c2ccc(cc2)c3cccc(c3)C(CC4CC4)C(=O)NCC#N
|
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| InChI |
InChI=1S/C25H30N4O/c1-28-13-15-29(16-14-28)23-9-7-20(8-10-23)21-3-2-4-22(18-21)24(17-19-5-6-19)25(30)27-12-11-26/h2-4,7-10,18-19,24H,5-6,12-17H2,1H3,(H,27,30)
|
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| InChIKey |
OMUUAINOWNXZJK-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | RANKL/RANK Signaling Pathway | ||||
| Osteoclast Signaling | |||||
| References | |||||
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