Drug Information
| Drug General Information | |||||
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| Drug ID |
DX6XGN
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| Drug Name |
6-((3S,6S,9S,14aR)-6-((1H-indol-3-yl)methyl)-9-benzyl-1,4,7,10-tetraoxotetradecahydropyrrolo[1,2-a][1,4,7,10]tetraazacyclododecin-3-yl)-N-hydroxyhexanamide
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| Synonyms |
CHEMBL1096985
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C33H40N6O6
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| Canonical SMILES |
ONC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CCCN2C(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc4c[nH]c5ccccc45)NC1=O
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| InChI |
InChI=1S/C33H40N6O6/c40-29(38-45)16-6-2-5-14-25-30(41)36-26(19-22-20-34-24-13-8-7-12-23(22)24)31(42)37-27(18-21-10-3-1-4-11-21)33(44)39-17-9-15-28(39)32(43)35-25/h1,3-4,7-8,10-13,20,25-28,34,45H,2,5-6,9,14-19H2,(H,35,43)(H,36,41)(H,37,42)(H,38,40)/t25-,26-,27-,28+/m0/s1
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| InChIKey |
OHPVTQHZRUJEEL-LAJGZZDBSA-N
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| Target and Pathway | |||||
| Target(s) | Histone deacetylase 6 | Target Info | [1587926] | ||
| Histone deacetylase 4 | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling Pathway | ||||
| Pathway Interaction Database | Signaling events mediated by HDAC Class II | ||||
| Signaling events mediated by HDAC Class Ihdac_classii_pathway:Signaling events mediated by HDAC Class II | |||||
| Signaling events mediated by HDAC Class III | |||||
| Signaling events mediated by HDAC Class I | |||||
| Sumoylation by RanBP2 regulates transcriptional repression | |||||
| Validated nuclear estrogen receptor alpha network | |||||
| WikiPathways | Ectoderm Differentiation | ||||
| Neural Crest Differentiation | |||||
| Cell CycleWP474:Endochondral Ossification | |||||
| Cardiac Hypertrophic Response | |||||
| miR-targeted genes in muscle cell - TarBase | |||||
| miR-targeted genes in lymphocytes - TarBase | |||||
| miR-targeted genes in epithelium - TarBase | |||||
| TarBasePathway | |||||
| Cell Cycle | |||||
| MicroRNAs in cardiomyocyte hypertrophy | |||||
| References | |||||
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