Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX6WSR
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| Drug Name |
(S)-3-Methyl-2-(3-m-tolyl-ureido)-pentanoic acid [(R)-1-formyl-2-(1H-indol-3-yl)-ethyl]-amide
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| Synonyms |
CHEMBL1790997
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C25H30N4O3
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| Canonical SMILES |
CC[C@@H](C)[C@H](NC(=O)Nc1cccc(C)c1)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C=O
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| InChI |
InChI=1S/C25H30N4O3/c1-4-17(3)23(29-25(32)28-19-9-7-8-16(2)12-19)24(31)27-20(15-30)13-18-14-26-22-11-6-5-10-21(18)22/h5-12,14-15,17,20,23,26H,4,13H2,1-3H3,(H,27,31)(H2,28,29,32)/t17-,20-,23+/m1/s1
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| InChIKey |
BUOGXVARMRYPBH-LLBVYWAGSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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