Drug Information

Drug General Information
Drug ID
DX6UOT
Drug Name
4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-(3-cyclohexyl-propionyl)-piperazine-2-carboxylic acid (pyridin-3-ylmethyl)-amide
Synonyms
CHEMBL201693
Indication Discovery agent Investigative [1587926]
Formula
C34H39BrClN5O2
Canonical SMILES
Clc1ccc2C(N3CCN(C(C3)C(=O)NCc4cccnc4)C(=O)CCC5CCCCC5)c6ncc(Br)cc6CCc2c1
InChI
InChI=1S/C34H39BrClN5O2/c35-27-17-26-10-9-25-18-28(36)11-12-29(25)33(32(26)38-21-27)40-15-16-41(31(42)13-8-23-5-2-1-3-6-23)30(22-40)34(43)39-20-24-7-4-14-37-19-24/h4,7,11-12,14,17-19,21,23,30,33H,1-3,5-6,8-10,13,15-16,20,22H2,(H,39,43)
InChIKey
XZAROMHMWKRDFK-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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