Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX6KAR
|
||||
| Drug Name |
N-((S)-1-((4S,7R)-7-methyl-3-oxo-1-(pyridin-2-ylsulfonyl)azepan-4-ylamino)-3-(4-methylcyclohexyl)-1-oxopropan-2-yl)furan-2-carboxamide
|
||||
| Synonyms |
CHEMBL1807698
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C27H36N4O6S
|
||||
| Canonical SMILES |
CC1CCC(C[C@H](NC(=O)c2occc2)C(=O)N[C@H]3CC[C@@H](C)N(CC3=O)S(=O)(=O)c4ccccn4)CC1
|
||||
| InChI |
InChI=1S/C27H36N4O6S/c1-18-8-11-20(12-9-18)16-22(30-27(34)24-6-5-15-37-24)26(33)29-21-13-10-19(2)31(17-23(21)32)38(35,36)25-7-3-4-14-28-25/h3-7,14-15,18-22H,8-13,16-17H2,1-2H3,(H,29,33)(H,30,34)/t18?,19-,20?,21+,22+/m1/s1
|
||||
| InChIKey |
UWIUSTCLSVVZSO-WHVLVZFFSA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.