Drug Information
| Drug General Information | |||||
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| Drug ID |
DX6GE4
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| Drug Name |
(S)-3-tert-butyl-N-(1-(cyanomethylamino)-3-(3-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl)-1-oxopropan-2-yl)-1-methyl-1H-pyrazole-5-carboxamide
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| Synonyms |
CHEMBL550872
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C23H27N7O3
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| Canonical SMILES |
Cc1oc(nn1)c2cccc(C[C@H](NC(=O)c3cc(nn3C)C(C)(C)C)C(=O)NCC#N)c2
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| InChI |
InChI=1S/C23H27N7O3/c1-14-27-28-22(33-14)16-8-6-7-15(11-16)12-17(20(31)25-10-9-24)26-21(32)18-13-19(23(2,3)4)29-30(18)5/h6-8,11,13,17H,10,12H2,1-5H3,(H,25,31)(H,26,32)/t17-/m0/s1
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| InChIKey |
BPIZQAAUSWBFNS-KRWDZBQOSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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