Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX6DXP
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| Drug Name |
(S)-N-((S)-1-cyano-2-phenylethyl)-2-cyclopropyl-2-((S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)biphenyl-4-yl)ethylamino)acetamide
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| Synonyms |
CHEMBL1290303
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C29H28F3N3O3S
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| Canonical SMILES |
CS(=O)(=O)c1ccc(cc1)c2ccc(cc2)[C@H](N[C@@H](C3CC3)C(=O)N[C@@H](Cc4ccccc4)C#N)C(F)(F)F
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| InChI |
InChI=1S/C29H28F3N3O3S/c1-39(37,38)25-15-13-21(14-16-25)20-7-11-23(12-8-20)27(29(30,31)32)35-26(22-9-10-22)28(36)34-24(18-33)17-19-5-3-2-4-6-19/h2-8,11-16,22,24,26-27,35H,9-10,17H2,1H3,(H,34,36)/t24-,26-,27-/m0/s1
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| InChIKey |
JLZPHDGPTVJCOI-URORMMCBSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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