Drug Information

Drug General Information
Drug ID
DX5UIR
Drug Name
4-{2-[4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-oxo-ethyl}-piperidine-1-carboxylic acid methylamide
Synonyms
CHEMBL369047
Indication Discovery agent Investigative [1587926]
Formula
C27H33BrClN5O2
Canonical SMILES
CNC(=O)N1CCC(CC(=O)N2CCN(CC2)C3c4ccc(Cl)cc4CCc5cc(Br)cnc35)CC1
InChI
InChI=1S/C27H33BrClN5O2/c1-30-27(36)34-8-6-18(7-9-34)14-24(35)32-10-12-33(13-11-32)26-23-5-4-22(29)16-19(23)2-3-20-15-21(28)17-31-25(20)26/h4-5,15-18,26H,2-3,6-14H2,1H3,(H,30,36)
InChIKey
XWCMUCOWDZOIAS-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.