Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX5HPS
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| Drug Name |
(S)-3-Methyl-2-(naphthalene-1-sulfonylamino)-pentanoic acid [(S)-1-(4-hydroxy-benzyl)-2-oxo-ethyl]-amide
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| Synonyms |
CHEMBL336415
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C25H28N2O5S
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| Canonical SMILES |
CCC(C)[C@H](NS(=O)(=O)c1cccc2ccccc12)C(=O)N[C@@H](Cc3ccc(O)cc3)C=O
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| InChI |
InChI=1S/C25H28N2O5S/c1-3-17(2)24(25(30)26-20(16-28)15-18-11-13-21(29)14-12-18)27-33(31,32)23-10-6-8-19-7-4-5-9-22(19)23/h4-14,16-17,20,24,27,29H,3,15H2,1-2H3,(H,26,30)/t17?,20-,24-/m0/s1
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| InChIKey |
VOLBXQXGWYNABH-OUSZHMKWSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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