Drug Information

Drug General Information
Drug ID
DX5FBN
Drug Name
4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazine-1,2-dicarboxylic acid 1-cyclohexylamide 2-[(3-imidazol-1-yl-propyl)-amide] 1-cyclohexylamide 2-{[2-(1-methyl-1H-imidazol-4-yl)-ethyl]-amide}
Synonyms
CHEMBL372162
Indication Discovery agent Investigative [1587926]
Formula
C32H39BrClN7O2
Canonical SMILES
Cn1cnc(CCNC(=O)C2CN(CCN2C(=O)NC3CCCCC3)C4c5ccc(Cl)cc5CCc6cc(Br)cnc46)c1
InChI
InChI=1S/C32H39BrClN7O2/c1-39-18-26(37-20-39)11-12-35-31(42)28-19-40(13-14-41(28)32(43)38-25-5-3-2-4-6-25)30-27-10-9-24(34)16-21(27)7-8-22-15-23(33)17-36-29(22)30/h9-10,15-18,20,25,28,30H,2-8,11-14,19H2,1H3,(H,35,42)(H,38,43)
InChIKey
CSHPNTOXXBGLLQ-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.