Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX4MBM
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| Drug Name |
N-((R)-3-(benzylthio)-1-oxo-1-((S)-1-(4-(trifluoromethoxy)phenylamino)propan-2-ylamino)propan-2-yl)morpholine-4-carboxamide
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| Synonyms |
CHEMBL215218
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C25H31F3N4O4S
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| Canonical SMILES |
C[C@@H](CNc1ccc(OC(F)(F)F)cc1)NC(=O)[C@H](CSCc2ccccc2)NC(=O)N3CCOCC3
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| InChI |
InChI=1S/C25H31F3N4O4S/c1-18(15-29-20-7-9-21(10-8-20)36-25(26,27)28)30-23(33)22(17-37-16-19-5-3-2-4-6-19)31-24(34)32-11-13-35-14-12-32/h2-10,18,22,29H,11-17H2,1H3,(H,30,33)(H,31,34)/t18-,22-/m0/s1
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| InChIKey |
RFIOGZCCMRDOHV-AVRDEDQJSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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