Drug Information

Drug General Information
Drug ID
DX3ZXS
Drug Name
4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazine-1,2-dicarboxylic acid 1-cyclohexylamide 2-[(3-imidazol-1-yl-propyl)-amide] 1-cyclohexylamide 2-{[3-(2-oxo-pyrrolidin-1-yl)-propyl]-amide}
Synonyms
CHEMBL372163
Indication Discovery agent Investigative [1587926]
Formula
C33H42BrClN6O3
Canonical SMILES
Clc1ccc2C(N3CCN(C(C3)C(=O)NCCCN4CCCC4=O)C(=O)NC5CCCCC5)c6ncc(Br)cc6CCc2c1
InChI
InChI=1S/C33H42BrClN6O3/c34-24-18-23-10-9-22-19-25(35)11-12-27(22)31(30(23)37-20-24)40-16-17-41(33(44)38-26-6-2-1-3-7-26)28(21-40)32(43)36-13-5-15-39-14-4-8-29(39)42/h11-12,18-20,26,28,31H,1-10,13-17,21H2,(H,36,43)(H,38,44)
InChIKey
YPOHNWIPWIEUFZ-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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