Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX3YXU
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| Drug Name |
Benzofuran-2-carboxylic acid {3-methyl-1-[2-oxo-3-(pyridine-2-sulfonylamino)-propylcarbamoyl]-butyl}-amide
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| Synonyms |
CHEMBL31381
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C23H26N4O6S
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| Canonical SMILES |
CC(C)C[C@H](NC(=O)c1oc2ccccc2c1)C(=O)NCC(=O)CNS(=O)(=O)c3ccccn3
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| InChI |
InChI=1S/C23H26N4O6S/c1-15(2)11-18(27-23(30)20-12-16-7-3-4-8-19(16)33-20)22(29)25-13-17(28)14-26-34(31,32)21-9-5-6-10-24-21/h3-10,12,15,18,26H,11,13-14H2,1-2H3,(H,25,29)(H,27,30)/t18-/m0/s1
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| InChIKey |
CJAWLAGZXPEOEW-SFHVURJKSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | RANKL/RANK Signaling Pathway | ||||
| Osteoclast Signaling | |||||
| References | |||||
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