Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX3TZL
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| Drug Name |
Naphthalene-2-carboxylic acid {(S)-2-cyclohexyl-1-[2-(4-methoxy-phenylamino)-ethylcarbamoyl]-ethyl}-amide
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| Synonyms |
CHEMBL264519
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C29H35N3O3
|
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| Canonical SMILES |
COc1ccc(NCCNC(=O)[C@H](CC2CCCCC2)NC(=O)c3ccc4ccccc4c3)cc1
|
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| InChI |
InChI=1S/C29H35N3O3/c1-35-26-15-13-25(14-16-26)30-17-18-31-29(34)27(19-21-7-3-2-4-8-21)32-28(33)24-12-11-22-9-5-6-10-23(22)20-24/h5-6,9-16,20-21,27,30H,2-4,7-8,17-19H2,1H3,(H,31,34)(H,32,33)/t27-/m0/s1
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| InChIKey |
YVIFJVYLCZWCDY-MHZLTWQESA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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