Drug Information

Drug General Information
Drug ID
DX3TH5
Drug Name
4'-(2-Amino-3-mercapto-propylamino)-[1,1';2',1'']terphenyl-3-carboxylic acid 14 (FTI-289)
Synonyms
FTI-289; CHEMBL55497
Indication Discovery agent Investigative [1587926]
Formula
C22H22N2O2S
Canonical SMILES
N[C@@H](CS)CNc1ccc(c2cccc(c2)C(=O)O)c(c1)c3ccccc3
InChI
InChI=1S/C22H22N2O2S/c23-18(14-27)13-24-19-9-10-20(16-7-4-8-17(11-16)22(25)26)21(12-19)15-5-2-1-3-6-15/h1-12,18,24,27H,13-14,23H2,(H,25,26)/t18-/m1/s1
InChIKey
LEOFHPLVHZUFJS-GOSISDBHSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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