Drug Information

Drug General Information
Drug ID
DX3JOR
Drug Name
2-{(R)-2-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-1-methyl-2-oxo-ethyl}-isoindole-1,3-dione
Synonyms
CHEMBL322847
Indication Discovery agent Investigative [1587926]
Formula
C30H26ClN3O3
Canonical SMILES
C[C@@H](N1C(=O)c2ccccc2C1=O)C(=O)N3CCC(=C4c5ccc(Cl)cc5CCc6cccnc46)CC3
InChI
InChI=1S/C30H26ClN3O3/c1-18(34-29(36)24-6-2-3-7-25(24)30(34)37)28(35)33-15-12-19(13-16-33)26-23-11-10-22(31)17-21(23)9-8-20-5-4-14-32-27(20)26/h2-7,10-11,14,17-18H,8-9,12-13,15-16H2,1H3/t18-/m1/s1
InChIKey
IXNNAWNZDWDBRL-GOSISDBHSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.