Drug Information

Drug General Information
Drug ID
DX3GMA
Drug Name
2-(1-Benzenesulfonyl-piperidin-4-yl)-1-[4-((R)-3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperidin-1-yl]-ethanone
Synonyms
CHEMBL313350
Indication Discovery agent Investigative [1587926]
Formula
C32H34Br2ClN3O3S
Canonical SMILES
Clc1cc(Br)c2[C@@H](C3CCN(CC3)C(=O)CC4CCN(CC4)S(=O)(=O)c5ccccc5)c6ncc(Br)cc6CCc2c1
InChI
InChI=1S/C32H34Br2ClN3O3S/c33-25-17-24-7-6-23-18-26(35)19-28(34)30(23)31(32(24)36-20-25)22-10-12-37(13-11-22)29(39)16-21-8-14-38(15-9-21)42(40,41)27-4-2-1-3-5-27/h1-5,17-22,31H,6-16H2/t31-/m1/s1
InChIKey
ZTMYMHHVUSBOAB-WJOKGBTCSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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