Drug Information

Drug General Information
Drug ID
DX3GLI
Drug Name
4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carboxylic acid {5-[3-(4-chloro-phenyl)-acryloylamino]-pentyl}-amide
Synonyms
CHEMBL417705
Indication Discovery agent Investigative [1587926]
Formula
C27H33Cl2N3O2
Canonical SMILES
CN1CC[C@@H]([C@H](C1)C(=O)NCCCCCNC(=O)\\C=C\\c2ccc(Cl)cc2)c3ccc(Cl)cc3
InChI
InChI=1S/C27H33Cl2N3O2/c1-32-18-15-24(21-8-12-23(29)13-9-21)25(19-32)27(34)31-17-4-2-3-16-30-26(33)14-7-20-5-10-22(28)11-6-20/h5-14,24-25H,2-4,15-19H2,1H3,(H,30,33)(H,31,34)/b14-7+/t24-,25+/m1/s1
InChIKey
VEWSJWHSMIMAHF-HKGQOMTBSA-N
Target and Pathway
Target(s) Sodium-dependent noradrenaline transporter Target Info [1587926]
Sodium-dependent serotonin transporter Target Info [1587926]
KEGG Pathway Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Adrenaline and noradrenaline biosynthesisP04373:5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
NRF2 pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsWP727:Monoamine Transport
SIDS Susceptibility Pathways
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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